Protease Inhibitors and Phosphatase Inhibitors
Cayman Chemical Radicicol, 12772-57-5, 1 mg
A natural product with antibiotic, antifungal, and antimalarial properties; binds and inhibits heat shock protein 90 (HSP90) with nanomolar affinity
Cayman Chemical LY294002, 154447-36-6, 10 mg
Molecular Formula C19H17NO3, Purity ≥98%, Formula Weight 307.3; A selective PI3K inhibitor with an IC50 value of 1.4 M.
StemRD THIAZOVIVIN RCK INHIBITR 25MG
Chemicals, Cell Culture Media and Reagents, Thiazovivin, ROCK inhibitor, 25 mg
Cayman Chemical L-NMMA (acetate), 53308-83-1, 25 mg
Molecular Formula C7H16N4O2 • C2H4O2, Purity ≥99%, Formula Weight 248.3, Synonyms: L-NG-monomethyl Arginine acetate; A relatively non-selective inhibitor of all NOS isoforms with Ki values 0.18, 0.4, and 6 M for nNOs (rat), eNOS (human), and iNOS (mouse), respectively.
Cayman Chemical Garcinol, 78824-30-3, 10 mg
An inhibitor of the HATs p300 and pCAF (IC50 = 7 and 5 μM, respectively) that also inhibits the HAT Gcn5; promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells; induces apoptosis in several types of cancer cells and has anti-inflammatory actions
Cayman Chemical E-64d, 88321-09-9, 1 mg
Molecular Formula C17H30N2O5, Purity ≥98%, Formula Weight 342.4, Synonyms: Aloxistatin, E-64c ethyl ester, EP 453, EST, Loxistatin, NSC 694281; An irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases; at 20-200 M arrests human epidermoid carcinoma A431 cells at mitotic metaphase; inhibits protease-resistant protein accumulation in scrapie-infected neuroblastoma cells (IC50 = 0.5 M).
Cayman Chemical Erlotinib, 183321-74-6, 250 mg
Molecular Formula C22H23N3O4, Purity ≥98%, Formula Weight 393.4, Synonyms: NSC 718781; A tyrosine kinase inhibitor which inhibits EGFR-associated kinase activity (IC50 = 2.5 M) and tumor growth in human HN5 tumor xenografts in mice with an ED50 value of 9 mg/kg; suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 M) and JAK2 mutant JAK2V617F positive hematopoietic progenitor cells (IC50 = 5 M).